I heard Broaddus say a draft can be screwed up even with a high pick. He used the Niners and their pick of Trey Lance as an example. That's true, but let's not forget that there are other rounds and picking top 5 in every round is very helpful. It also allows a team to drop back and pick up more picks.
The bottom line is a draft can be screwed up no matter where a team is picking, but I like my odds better if I'm picking first.
In fact, if I had the top pick, unless there was a Troy Aikman, a John Elway, or a true blue chipper, I'd try to accumulate as many bites of the apple as possible in each round. However, not repeating the mistake Jerry made in 2009 in which he didn't pick anyone, I think, until round 3 (Jason Williams).